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杨林蔚
讲师（高校）
海洋学院
行政职务：
院团委副书记
技术职称：
讲师（高校）
最后学位：
理学博士学位
电    话：
15800036487
电子邮箱：
yanglinwei@fafu.edu.cn
办公地点：
海洋学院406
通讯地址：
福建省福州市仓山区上下店路15号
邮    编：
350108

您是第10 位访问者

  • 杨林蔚，男，中共党员，讲师，硕士生导师，福建省高层次C类人才。主要研究方向为水生生物抗逆、抗病机制及病害防控技术；以第一/通讯作者（含共同）在Reviews in Aquaculture，Journal of Virology，Microbiology Spectrum，International Journal of Biological Macromolecules等SCI杂志发表21篇，申请发明专利4项。主持国家、省部级科研项目5项，高校青年教师培育项目1项。担任国际期刊Fishes和Frontiers in Immunology客座编辑，并担任珠海市海洋渔业专家库专家。

  • 教育经历

    2011-09至2015-07，西北农林科技大学动物科技学院，本科。

    2015-09至2020-07，中山大学生命科学学院，博士（直博，优生优培），导师：何建国教授。

  • 工作经历

    2020-07至2023-02，中山大学，生命科学学院，博士后；

    2023-02至2023-12，中山大学，生命科学学院，特聘副研究员；

    2024-03-至今，福建农林大学，海洋学院，讲师。


  • 荣誉及奖励

    1.福建省C类人才（2024）


  • 教学活动

    教学理念：在教学科研中秉承“以人为本”的理念，突出学生的主体地位，强化学生实践与应用能力的培养，引导学生树立正确的人生观、价值观，全方位为我国海洋事业培养高素质人才。

    1.第二指导学生获得福建省“互联网+”大学生创新创业大赛（2024）银奖；

    2.第一指导学生获得“燕之屋杯”第十一届福建省大学生食品创新创意大赛（2024）三等奖；

    3.第一指导学生获得中国国际大学生创新大赛（2024）福建农林大学校赛铜奖。


    思政项目：

    1.项目负责人获得福建农林大学2025年度思想政治工作精品项目1项。高质量党建引领产学研融合，培育新时代水产英才立项1项

    • 研究领域

      水生动物免疫与病害控制

    开授课程

      承担本科生课程《海洋生物学基础》、《海产品加工工艺学》。

    科研项目

    1. 国家自然科学基金-青年科学基金项目, 32202974，2023-2025，30万，在研，主持。

    2. 国家重点研发计划，2023YFD2401702，2023-2027，40万，在研，课题2子课题负责人。

    3. 广东省区域联合基金-青年基金，2021A1515110900，2021-2024，10万，结题，主持。

    4. 广东省自然科学基金-面上项目，2023A1515010864，2023-2025，10万，在研，主持。

    5. 福建省自然科学基金-面上项目，2024J01432，2024-2027，10万，在研，主持。

    6. 青年教师培育项目（中山大学），22qntd2615，7.45万，结题，主持。


    论文著作

    第一或通讯作者（含共同）21篇(#共同第一作者；*共同通讯作者)

    1. Linwei Yang, Yushi Gan, Hengwei Deng, Jianguo He*, Xiaopeng Xu*. Recent Research Advances on the Hippo‐Yki Pathway of Crustaceans: Current Knowledge and Potential Applications in Crustacean Aquaculture. Reviews in Aquaculture. 2025, 17:e12955.

    2. Siyou Huang#, Linwei Yang#, Rui Zheng, Shaoping Weng, Jianguo He*, Junfeng Xie*. Nervous necrosis virus capsid protein and Protein A dynamically modulate the fish cGAS-mediated IFN signal pathway to facilitate viral evasion. Journal of Virology. 2024 Jun 18:e0068624.

    3. Linwei Yang; Zi-ang Wang; Ran Geng; Hengwei Deng; Shengwen Niu; Hongliang Zuo; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. White Spot Syndrome Virus (WSSV) Inhibits Hippo Signaling and Activates Yki to Promote Its Infection in Penaeus vannamei. Microbiology Spectrum, 2022:e0236322.

    4. Linwei Yang#; Siyou Huang#; Zi-ang Wang; Deyu Han; Yushi Gan; Ran Geng; Hongliang Zuo; Zhixun Guo; Shaoping Weng; Jianguo He; Xiaopeng Xu; Oral delivery of bacteria expressing wsv108 gene-specific dsRNA protects shrimp from white spot syndrome virus (WSSV) infection, International Journal of Biological Macromolecules, 2024, 261:129840.

    5. Linwei Yang#; Zi-ang Wang#; Ran Geng; Shengwen Niu; Hongliang Zuo; Zhixun Guo; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. The Hippo-Yki Signaling Pathway Positively Regulates Immune Response against Vibrio Infection in Shrimp. International Journal of Molecular Sciences. 2022, 23(19):11897.

    6. Linwei Yang; Mengting Luo; Zhixun Guo; Hongliang Zuo; Shaoping Weng; Jianguo He; Xiaopeng Xu*. A shrimp gene encoding a single WAP domain (SWD)-containing protein regulated by JAK-STAT and NF-kappaB pathways. Developmental & Comparative Immunology, 2020, 104:103537.

    7. Linwei Yang; Shengwen Niu; Jiefeng Gao; Hongliang Zuo; Jia Yuan; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. A single WAP domain (SWD)-containing protein with antiviral activity from Pacific white shrimp Litopenaeus vannamei. Fish & Shellfish Immunology, 2018, 73:167-174.

    8. Linwei Yang#; Zi-ang Wang#; Hongliang Zuo; Ran Geng; Zhixun Guo; Shengwen Niu; Shaoping Weng; Jianguo He; Xiaopeng Xu*. The LARK protein is involved in antiviral and antibacterial responses in shrimp by regulating humoral immunity. Developmental & Comparative Immunology, 2021, 114:103826.

    9. Linwei Yang#; Zi-ang Wang#; Hongliang Zuo; Zhixun Guo; Shaoping Weng; Jianguo He; Xiaopeng Xu*. Wnt5b plays a negative role in antibacterial response in Pacific white shrimp Penaeus vannamei. Developmental & Comparative Immunology, 2022, 133:104411.

    10. Linwei Yang; Mengting Luo; Jianhui He; Hongliang Zuo; Shaoping Weng; Jianguo He; Xiaopeng Xu*. A JAK-STAT pathway target gene encoding a single WAP domain (SWD)-containing protein from Litopenaeus vannamei. Fish & Shellfish Immunology, 2019, 89:555-563.

    11. Linwei Yang#; Zi-ang Wang#; Ran Geng; Shengwen Niu; Hongliang Zuo; Shaoping Weng; Jianguo He; Xiaopeng Xu*. A kelch motif-containing protein KLHDC2 regulates immune responses against Vibrio parahaemolyticus and white spot syndrome virus in Penaeus vannamei. Fish & Shellfish Immunology, 2022, 127:187-194.

    12. Linwei Yang, Deyu Han, Zi-ang Wan, Nuo Chen, Hongliang Zuo, Zhixun Guo, Menghuang X, Shaoping Weng, Jianguo He, Xiaopeng Xu*. The Hippo-Yki pathway downstream transcription factor Scalloped negatively regulates immune defense against Vibrio parahaemolyticus infection in shrimp. Fish & Shellfish Immunology, 2023, 139:108917.

    13. Linwei Yang, Zi-ang Wang, Yushi Gan, Hongliang Zuo, Hengwei Deng, Shaoping Weng, Jianguo He*, Xiaopeng Xu*. Basigin binds bacteria and activates Dorsal signaling to promote antibacterial defense in Penaeus vannamei. Fish & Shellfish Immunology, 2023, 142:109123.

    14. Liang Zhiwei#; Linwei Yang#; Jiefu Zheng; Hongliang Zuo; Shaoping Weng; Jianguo He; Xiaopeng Xu*. A low-density lipoprotein receptor (LDLR) class A domain-containing C-type lectin from Litopenaeus vannamei plays opposite roles in antibacterial and antiviral responses. Developmental & Comparative Immunology, 2019, 92:29-34.

    15. Shengwen Niu#; Linwei Yang#; Hongliang Zuo; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. A chitinase from pacific white shrimp Litopenaeus vannamei involved in immune regulation. Developmental & Comparative Immunology, 2018, 85:161-169.

    16. Shengwen Niu#; Linwei Yang#; Ran Geng; Hongliang Zuo; Zhixun Guo; Shaoping Weng; Jianguo He; Xiaopeng Xu*. A double chitin catalytic domain-containing chitinase targeted by c-Jun is involved in immune responses in shrimp. Developmental & Comparative Immunology, 2020, 113:103808.

    17. Mengting Luo#; Linwei Yang#; Zi-ang Wang; Hongliang Zuo; Shaoping Weng; Jianguo He; Xiaopeng Xu*. A novel C-type lectin with microbiostatic and immune regulatory functions from Litopenaeus vannamei. Fish & Shellfish Immunology, 2019, 93:361-368.

    18. Hongliang Zuo#; Linwei Yang#; Jiefu Zheng; Ziqi Su; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. A single C4 Zinc finger-containing protein from Litopenaeus vannamei involved in antibacterial responses. Fish & Shellfish Immunology, 2018, 81:493-501.

    19. Zi-ang Wang#; Linwei Yang#; Zexu Zhao; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. A novel perlucin with immune regulatory functions protects Litopenaeusvannamei against Vibrio parahaemolyticus infection. Fish & Shellfish Immunology, 2024, 155:110028.

    20. Xiyu Huang#; Mingming Zhao#; Jieyu Huang; Mingjian Liu; Linwei Yang*; Chuanqi Wang*. DRAM2 inhibits white spot syndrome virus infection via activating autophagy in Penaeus vannamei. Fish & Shellfish Immunology, 2025, 160:110240.

    21. Jianchun Shao#, Qingyin Zheng#, Zhengbang Chen, Wenbo Zhu, Qiulei Ren, Kai Yuan*, Linwei Yang*. Enzyme-Treated Soybean Meal Serves as an Effective Alternative to Fishmeal in the Diet of the Shrimp Penaeus vannamei. Aquaculture Nutrition, 2025, 2025:2312302.

    其他作者15篇

    1. Zi-ang Wang#; Jiefu Zheng#; Linwei Yang; Hongliang Zuo; Shengwen Niu; Shaoping Weng; Jianguo He; Xiaopeng Xu*. Wnt11 positively regulates immune defense against Vibrio parahaemolyticus but promotes white spot syndrome virus infection in Litopenaeus vannamei. Aquaculture, 2021, 542:736910.

    2. Jiefeng Gao#; Hongliang Zuo#; Linwei Yang; Jianhui He; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. Long-term influence of cyanobacterial bloom on the immune system of Litopenaeus vannamei. Fish & Shellfish Immunology, 2017, 61:79-85.

    3. Xiaopeng Xu; Jia Yuan; Linwei Yang; Shaoping Weng; Jianguo He*; Hongliang Zuo*. The Dorsal/miR-1959/Cactus feedback loop facilitates the infection of WSSV in Litopenaeus vannamei. Fish & Shellfish Immunology, 2016, 56:397-401.

    4. Hongliang Zuo#; Jia Yuan#; Linwei Yang; Jiefu Zheng; Shaoping Weng; Jianguo He; Xiaopeng Xu*. Identification of the thioredoxin-related protein of 14 kDa (TRP14) from Litopenaeus vannamei and its role in immunity. Fish & Shellfish Immunology, 2018, 80:514-520.

    5. Hongliang Zuo#; Jia Yuan#; Linwei Yang; Zhiwei Liang; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. Characterization and immune function of the thioredoxin-interacting protein (TXNIP) from Litopenaeus vannamei. Fish & Shellfish Immunology, 2019, 84:20-27.

    6. Hongliang Zuo; Jia Yuan; Shengwen Niu; Linwei Yang; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. A molting-inhibiting hormone-like protein from Pacific white shrimp Litopenaeus vannamei is involved in immune responses. Fish & Shellfish Immunology, 2018, 72:544-551.

    7. Hongliang Zuo; Xinxin Liu; Mengting Luo; Linwei Yang; Zhiming Zhu; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. miR-10c Facilitates White Spot Syndrome Virus Infection by Targeting Toll3 in Litopenaeus vannamei. Frontiers in immunology, 2021, 12:733730.

    8. Hongliang Zuo#; Kejia Weng#; Mengting Luo; Linwei Yang; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. A MicroRNA-1-Mediated Inhibition of the NF-κB Pathway by the JAK-STAT Pathway in the Invertebrate Litopenaeus vannamei. Journal of Immunology, 2020, 204:2918-2930.

    9. Huang Siyou#; Zheng Rui#; Kang Yiling; Yang Linwei; Gao Jie; Liu Qinging; Weng Shaoping; He Jianguo; Xie Junfeng. Orange-spotted grouper IFNh response to NNV or MSRV and its potential antiviral activities. Fish & Shellfish Immunology, 2023, 145:109345.

    10. Huang Siyou, Kang Yiling, Zheng Rui, Yang Linwei, Gao Jie, Tang Wanting, Jiang Jing, He Jianguo, Xie Junfeng. Two cytokine receptor family B (CRFB) members in orange-spotted grouper Epinephelus coioides, EcCRFB3 and EcCRFB4, negatively regulate interferon immune responses to assist nervous necrosis virus replication. Fish & Shellfish Immunol. 2024 Jun 22; 151:109718.

    11. Hongliang Zuo#; Jiefeng Gao#; Jia Yuan; Hengwei Deng; Linwei Yang; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. Fatty acid synthase plays a positive role in shrimp immune responses against Vibrio parahaemolyticus infection. Fish & Shellfish Immunology, 2017, 60:282-288.

    12. Mengting Luo#; Xiaopeng Xu#; Xinxin Liu; Wenjie Shen; Linwei Yang; Zhiming Zhu; Shaoping Weng; Jianguo He*; Hongliang Zuo*. The Non-Receptor Protein Tyrosine Phosphatase PTPN6 Mediates a Positive Regulatory Approach from the Interferon Regulatory Factor to the JAK/STAT Pathway in Litopenaeus vannamei. Frontiers in immunology, 2021, 13:913955.

    13. Qianhui Liang#; Jiefu Zheng#; Hongliang Zuo; Chaozheng Li; Shengwen Niu; Linwei Yang; Muting Yan; Shaoping Weng; Jianguo He*; Xiaopeng Xu*. Identification and characterization of an interleukin-16-like gene from pacific white shrimp Litopenaeus vannamei. Developmental & Comparative Immunology, 2017, 74:49-59.

    14. Shengwen Niu#, Yuening Zhu#, Ran Geng, Nuo Chen, Hongliang Zuo, Linwei Yang, Shaoping Weng, Jianguo He, Xiaopeng Xu*. A novel chitinase Chi6 with immunosuppressive activity promotes white spot syndrome virus (WSSV) infection in Penaeus vannamei. Fish Shellfish Immunol. 2023 Jan;132:108450.

    15. Shengwen Niu#; Yuening Zhu#; Ran Geng; Nuo Chen; Mengting Luo; Hongliang Zuo; Linwei Yang; Shaoping Weng; Jianguo He; Xiaopeng Xu*. A novel Toll receptor from Pacific white shrimp Penaeus vannamei is involved in immune defense against Vibrio parahaemolyticus infection. Aquaculture, 2023, 569:739396.

    科技成果

    专利

    1. 杨林蔚,徐晓鹏,何建国,翁少萍,王子昂;三氧化二铁纳米颗粒在富集病毒中的应用;申请号：2023101467208；2023年02月20日；

    2. 杨林蔚,徐晓鹏,何建国,左洪亮,翁少萍,王子昂,韩德宇;一种用于干扰wsv108基因表达的重组菌及其应用。申请号：2023112409121；2023年09月22日；

    3. 谢俊锋,黄思悠,杨林蔚,郑瑞，翁少萍，何建国;一种斜带石斑鱼IFNh蛋白及其在制备提高抗病毒能力的产品中的应用。申请号：2023114526670；2023年11月02日；

    4. 谢俊锋,何建国,高杰,杨林蔚;一种基于RT-RAA和双CRISPR/Cas12a的神经坏死病毒检测试剂盒。申请号：2024109632104；2024年07月18日。